Beginning in 1925, intrastate bus service was regulated by the South Carolina Railroad Commission. The earliest Annual Report listing bus companies was in 1928, in order of the Certificate of Convenience and Necessity numbers. Approximate years when bus routes were introduced are only available for years 1929 through 1934.
Apparently, certificate numbers had a letter added when sold, or the bus company was part of a merger or renaming.
Certificate Name of Operating No. Change Operator Between 1A Camel City Coach Co. Columbia-Charlotte NC 1B 1932 Atlantic Greyhound Lines of NC Columbia-Charlotte NC 1C 1934 Atlantic Greyhound Lines Columbia-Charlotte NC 2A Camel City Coach Co. Camden-Florence 2B 1932 Atlantic Greyhound Lines of NC Camden-Florence 2C 1934 Atlantic Greyhound Lines Camden-Florence 4A Camel City Coach Co. Columbia-Augusta GA 4B 1932 Atlantic Greyhound Lines of NC Columbia-Augusta GA 4C 1934 Atlantic Greyhound Lines Columbia-Augusta GA 5A Camel City Coach Co. Columbia-Rock Hill 5B 1932 Atlantic Greyhound Lines of NC Columbia-Rock Hill 5C 1934 Atlantic Greyhound Lines Columbia-Rock Hill 6 Hayes Bus Lines Columbia-Greenville 6B 1931 Camel City Coach Co. Columbia-Greenville 6C 1932 Atlantic Greyhound Lines of NC Columbia-Greenville 6D 1934 Atlantic Greyhound Lines Columbia-Greenville 7 Eagle Bus Line Greenville-Columbia 7A 1933 Eagle Bus Line Greenville-Columbia 8 Inter-Carolinas Motor Bus Co. Spartanburg-Gastonia NC 8A 1929 Queen City Coach Co. Spartanburg-Gastonia NC 8B 1932 Queen City Lines Spartanburg-Charlotte NC 8C 1934 Old South Lines Spartanburg-Charlotte NC 9C Camel City Coach Co. Rock Hill-Charlotte NC 9D 1932 Atlantic Greyhound Lines of NC Rock Hill-Charlotte NC 9E 1934 Atlantic Greyhound Lines Rock Hill-Charlotte NC 10 Inter-Carolinas Motor Bus Co. Rock Hill-Gastonia NC 11 Inter-Carolinas Motor Bus Co. Spartanburg-Greenville 11A 1929 Queen City Coach Co. Spartanburg-Greenville 11B 1932 Queen City Lines Spartanburg-Greenville 11C 1934 Old South Lines Spartanburg-Greenville 12A Red Top Bus Line Greenv.-Hendersonv. (disc. 1930) 14A Piedmont Transportation Co. Union-Lancaster 16 Red Dot Bus Line Spartanburg-Jonesville-Union 16A 1931 Carolina Scenic Coach Line Spartanburg-Jonesville-Union 17 J. R. Griffith Buffalo-Union (disc. 1929) 18 McDuff Turner Spartanburg-Tyron NC 19 McDuff Turner Spartanburg-Greenwood 20C Camel City Coach Co. Columbia-Charleston 20D 1932 Atlantic Greyhound Lines of NC Columbia-Charleston 20E 1934 Atlantic Greyhound Lines Columbia-Charleston 23A Red Top Bus Line Greenville-Anderson 23B 1931 Red Top Bus Line Greenville-Anderson 25A Inter-State Scenic Coach Line Greenville-Brevard (disc. 1934) 26 Walker & Smith Saluda-Greenwood 26A 1929 Inter-Carolinas Motor Bus Co. Saluda-Greenwood 30 J. M. Tolbert Newberry-Union 30A 1934 Hamish Turner Newberry-Union 31 Hamrick & Company Spartanburg-Rutherfordton NC 31A 1931 Carolina Scenic Coach Line Spartanburg-Rutherfordton NC 32A Augusta-Greenville Bus Line Augusta GA-Greenv. (disc. 1930) 33 Red Dot Bus Line Spartanburg-Glenn Springs-Union 33A 1931 Carolina Scenic Coach Line Spartanburg-Glenn Springs-Union 35B Greenville-Augusta Coach Line Greenville-Augusta (disc. 1930) 38A S. W. Hopper Great Falls-Chester (disc. 1931) 39B Stokes Bus Line Columbia-Springf. (disc. 1932) 43B Inter-Carolinas Motor Bus Co. Greenville-Toccoa GA 43C 1929 Queen City Coach Co. Greenville-Toccoa GA 43D 1932 Queen City Lines Greenville-Toccoa GA 43E 1934 Old South Lines Greenville-Toccoa GA 44 F. L. Alexander Anderson-Walhalla 44A 1931 Edwards & Holleman Anderson-Walhalla 45B Inter-Carolinas Motor Bus Co. Anderson-Athens GA 48 Spartanburg Bus Co. Spartanburg-suburbs 48A 1929 Southern Public Utilities Co. Spartanburg-suburbs 51 G. S. Pierce Cottagev-Charleston (disc. 1932) 52 Thompson Transfer Co. Charleston-Savannah GA 52A 1930 Camel City Coach Co. Charleston-Savannah GA 52B 1932 Atlantic Greyhound Lines of NC Charleston-Savannah GA 52C 1934 Atlantic Greyhound Lines Charleston-Savannah GA 57A Thompson Transfer Co. Hog Island Ferry-Isle of Palms 57B 1929 Thompson Transfer Co. Isle of Palms-Charleston 58 Thompson Transfer Co. Charleston-Summerville 59 Thompson Transfer Co. Charleston-Florence 59A 1929 Camel City Coach Co. Charleston-Florence 59B 1932 Atlantic Greyhound Lines of NC Charleston-Florence 59C 1934 Atlantic Greyhound Lines Charleston-Florence 62 J. H. Anderson Conway-Marion 63 W. P. Cartrette Conway-Marion (disc. 1931) 65A J. H. Anderson Conway-Georgetown (disc. 1929) 66A Carolina Motor Bus Lines Newberry-Anderson 67 Red Dot Bus Line Spartanburg-Clinton 67A 1931 Carolina Scenic Coach Line Spartanburg-Clinton 69 Hayes Bus Lines Columbia-Saluda Dam (disc. 1931) 70 Whitmire-Greenwood Bus Line Whitmire-Greenwood 70A 1929 Inter-Carolinas Motor Bus Co. Whitmire-Greenwood 74A Charles T. Hayes Columbia-Florence 74B 1930 Camel City Coach Co. Columbia-Florence 74C 1932 Atlantic Greyhound Lines of NC Columbia-Florence 74D 1934 Atlantic Greyhound Lines Columbia-Florence 76 Inter-Carolinas Motor Bus Co. York-Chester 77 Stokes Bus Line Barnwell-Columbia 78 Walker & Smith Saluda-Batesburg 78A 1929 Inter-Carolinas Motor Bus Co. Saluda-Batesburg 79 Spartanburg-Augusta Bus Co. Clinton-Augusta GA 79A 1932 Carolina Scenic Coach Line Clinton-Augusta GA 80B Piedmont Transportation Co. Camden-Lake City (disc. 1929) 81 McCormick Motor Line Greenwood-Augusta 81A 1931 Skyland Stages Greenwood-Augusta 81B 1934 Atlantic Greyhound Lines Greenwood-Augusta 82A Columbia Bus Co. Blanding-Andrews (disc. 1929) 83 Piedmont Transportation Co. Lancaster-Monroe NC 84 Chester & Greenwood Bus Line Whitmire-Chester 84A 1929 Inter-Carolinas Motor Bus Co. Whitmire-Chester 85 Albermarle-Salisbury-Wadesboro Bus Line Wadesboro NC-Cheraw (disc. 1929) 86 Electric City Bus Line Anderson-Calhoun F. (disc. 1930) 87 Shipman-Wilson Bus Line Greenville-Ware Shoals 87A 1929 Red Top Bus Line Williamston-Greenville 89A 1929 Inter-Carolinas Motor Bus Co. Batesburg-Columbia 90 1929 Inter-Carolinas Motor Bus Co. York-Charlotte NC 91 1929 Inter-Carolinas Motor Bus Co. Greenwood-Athens GA 92 1929 Red Top Bus Line Anderson-Williamston 93 1929 Queen City Coach Co. Florence-Lumberton NC 94 1929 Piedmont Transportation Co. Enoree-Greenville 95 1929 E. A. Bissonette Charleston-North Charleston 96 1929 Camel City Coach Co. Belvedere-Augusta GA 96A 1932 Atlantic Greyhound Lines of NC Belvedere-Augusta GA 97A 1929 Piedmont Transportation Co. Enoree-Union 98 1929 Price Transportation Lines Charleston-Edisto (disc. 1931) 99 1929 Greenwood-South Greenwood Bus Line Greenwood-S. Greenw (disc. 1931) 100 1929 Red Dot Bus Line Union-Columbia 100A 1931 Carolina Scenic Coach Line Union-Columbia 101 1930 Thompson Transfer Co. Charleston-Conway 101B 1932 East Coast Stages Charleston-Conway (disc. 1934) 102 1930 White Stage Line Augusta-Charleston 102A 1934 Southeastern Stages Augusta-Charleston 103 1930 Camel City Coach Co. NC State Line-Darlington 103A 1932 Atlantic Greyhound Lines of NC NC State Line-Darlington 103B 1934 Atlantic Greyhound Lines NC State Line-Darlington 104 1930 Camel City Coach Co. NC State Line-Camden 104A 1932 Atlantic Greyhound Lines of NC NC State Line-Camden 104B 1934 Atlantic Greyhound Lines NC State Line-Camden 105 1930 Skyland Stages NC-GA State Line via US 25 105A 1934 Atlantic Greyhound Lines NC-GA State Line via US 25 106 1930 Isaac Fireall Bellinger-Savannah (disc. 1932) 107 1930 Walterboro Bus Co. Walterboro-Green P. (disc. 1932) 108 1930 Safety Transit Wilmington NC-Charleston 108A 1932 East Coast Stages Wilmington NC-Charleston 108B 1934 East Coast Stages Wilmington NC-Charleston 109 1930 Garden City Coach Co. Augusta GA-Savannah GA 109A 1934 Southeastern Stages Augusta GA-Savannah GA 110 1931 Blufton-Savannah Bus Line Blufton-Savannah (disc. 1932) 111 1931 Inter-Carolinas Motor Bus Co. Columbia-Savannah 111A 1932 Columbia-Savannah Coach Line Columbia-Savannah 112 1931 Camel City Coach Co. Yemassee-Beaufort 112A 1932 Atlantic Greyhound Lines of NC Yemassee-Beaufort 113A 1932 East Coast Stages NC State Line-Charleston 114B 1932 Atlantic Greyhound Lines of NC Charleston-GA State Line 114C 1934 Atlantic Greyhound Lines Charleston-GA State Line 115A 1932 East Coast Stages NC-GA via Columbia (disc. 1934) 116 1932 Carolina Coach Co. NC-GA via Greenv. (disc. 1934) 117 1932 Stokes Bus Line Williston-Augusta GA 118 1932 East Coast Stages Charleston-GA State Line via US 17 119 1932 East Coast Stages NC-GA State Line Augusta via US 1 120 1933 Fort Sumter Navigation Tours Mt. Pleasant Ferry Wharf 121 1933 East Coast Stages Bennettsville-Cheraw 122 1933 East Coast Stages NC-GA State Line via US 401-17 123 1934 Fort Sumter Navigation Tours Ferry Wharf-Sullivans Island 124 1934 J. J. Cook Anderson-Calhoun Falls 125 1934 Atlantic Greyhound Lines Sumter-Camden 126 1934 Eagle Bus Line Abbeville-Greenville 127 1934 Atlantic Greyhound Lines Travellers Rest-Brevard NC 128 1934 Queen City Coach Co. Bennettsville-Charlotte NC 129 1934 Hamish Turner Newberry-Saluda